A Study on the Effect of the Energy of Consciousness Healing Treatment on Physicochemical and Thermal Properties of Vitamin D3 (Cholecalciferol)

Vitamin D3 or cholecalciferol is a secosteroid nutraceutical used for the prevention and treatment of vitamin D deficiency. The objective of this study was to investigate the impact of The Trivedi Effect® - Energy of Consciousness Healing Treatment on the physicochemical and thermal properties of cholecalciferol using PXRD, PSA, DSC, and TGA/DTG analysis. Cholecalciferol was divided into two parts, one part of cholecalciferol was considered as control (no Biofield Treatment was provided), while second part received The Trivedi Effect® - Biofield Energy Healing Treatment remotely by a renowned Biofield Energy Healer, Alice Branton. The PXRD analysis exhibited that the relative intensities of characteristic diffraction peak in the Alice’s treated cholecalciferol were significantly altered from -28.21% to 54.16% compared with the control sample. The crystallite size of the treated sample was altered from -40.02% to 83.20% compared with the control sample. The particle size values at d10, d50, d90, and D(4, 3) in Alice’s treated sample were significantly reduced by 33.48%, 23.82%, 18.61%, and 22.08%, respectively compared to the control sample. The specific surface area of treated cholecalciferol was significantly increased by 32.72% compared to the control sample. The DSC analysis demonstrated that the melting point of the treated sample was higher by 0.24% with an enhanced latent heat of fusion (?H) by 3.54% compared to the control sample. The decomposition temperature of the treated cholecalciferol was increased by 0.12% with a significant increase of the enthalpy of decomposition by 5.85% compared to the control sample. The melting temperature and ?H of a second broad endothermic peak in the treated sample were increased by 0.18% and 73.87%, respectively compared to the control sample. The TGA analysis revealed that the weight loss in the treated sample was decreased compared with the control sample. The DTG analysis indicated that the maximum thermal degradation temperature of the treated cholecalciferol was increased by 3.23% compared to the control sample. Overall, the thermal analysis indicated that the thermal stability of the treated cholecalciferol was improved compared to the control sample. Thus, The Trivedi Effect® might lead to produce a polymorphic form of cholecalciferol which might have the improved solubility, bioavailability, and thermally stability as compared with the untreated sample. The Biofield Energy Treated cholecalciferol would be beneficial to design better nutraceutical and pharmaceutical formulations, which could provide better therapeutic response against vitamin D deficiency i.e. rickets, osteoporosis, cancer, diabetes mellitus, etc.

The present article inferred that The Trivedi Effect® - Energy of Consciousness Healing Treatment exhibited the significant impact on the relative intensities and crystallite size of the characteristic diffraction peaks, particle size, surface area, and thermodynamic stability of cholecalciferol. Relative intensities of the characteristic diffraction peak in the Alice’s Biofield Energy Treated cholecalciferol were significantly changed from -28.21 to 54.16% compared with the control sample. Consequently, the crystallite sizes of the Biofield Energy Treated sample was altered from -40.02% to 83.20% compared with the control sample. The particle size values at d10, d50, d90, and D(4, 3) in Alice’s Biofield Energy Treated sample were significantly decreased by 33.48%, 23.82%, 18.61%, and 22.08%, respectively compared to the control sample. The specific surface area (SSA) of Biofield Energy Treated cholecalciferol was significantly increased by 32.72% with respect to the control sample. The DSC analysis demonstrated that the melting point of the Biofield Energy Treated sample was higher by 0.24% with an increased latent heat of fusion (?H) by 3.54% compared with the control sample. The decomposition temperature and the enthalpy of decomposition of the Biofield Energy Treated cholecalciferol were increased by 0.12%, and 5.85%, respectively compared with the control sample. The melting temperature and ?H of a broad endothermic peak in the Biofield Energy Treated sample were increased by 0.18% and 73.87%, respectively compared to the control sample. The TGA thermograms of both the control and Biofield Energy Treated samples exhibited a major weight loss from ~150°C to 350°C. The weight loss in the Biofield Energy Treated sample was decreased compared with the control sample. The DTG analysis indicated that the Tmax of the treated cholecalciferol was increased by 3.23% compared to the control sample. Overall, the thermal analysis indicated that the thermodynamic stability of the Biofield Energy Treated cholecalciferol was significantly enhanced compared to the control sample. Thus, the Energy of Consciousness Healing Treatment (The Trivedi Effect® ) might lead to produce a polymorphic form of cholecalciferol which might have the improved solubility, bioavailability, and thermodynamic stability as compared with the untreated sample. The Biofield Energy Treated cholecalciferol would be very suitable to design better nutraceutical and pharmaceutical formulations which might offer better therapeutic response against vitamin D deficiency i.e. rickets, osteoporosis, cancer, diabetes mellitus, mental disorders, cardiovascular diseases, multiple sclerosis, infections.